Table 2

Outcomes measured in a randomized controlled trial of recombinant activated factor VII

Blunt trauma

Penetrating trauma

Outcomes

rFVIIa

Placebo

P

rFVIIa

Placebo

P

Mortality

25%

30%

0.58

24%

28%

0.69

MOF/ARDS

10%

23%

0.07

7%

17%

0.11

ICU-free days

13

8

0.18

24

20

0.26

Ventilation-free days

17

14

0.44

26

22

0.17

Both intensive care unit (ICU)-free and ventilator-free days were measured for 30 days. ARDS, acute respiratory distress syndrome; MOF, multiple organ failure; rFVIIa, activated recombinant factor VII.

Mohr et al. Critical Care 2005 9(Suppl 5):S37   doi:10.1186/cc3784