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<art>
   <ui>cc1440</ui>
   <ji>CCJ</ji>
   <fm>
      <dochead>Meeting abstract</dochead>
      <bibl>
         <title>
            <p>Oesophageal Doppler monitoring of descending aortic blood flow velocity during off-pump coronary artery bypass surgery</p>
         </title>
         <aug>
            <au id="A1">
               <snm>Kodakat</snm>
               <fnm>SK</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A2">
               <snm>Delaguila</snm>
               <fnm>M</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A3">
               <snm>Trivedi</snm>
               <fnm>U</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A4">
               <snm>Kong</snm>
               <fnm>R</fnm>
               <insr iid="I1"/>
            </au>
         </aug>
         <insg>
            <ins id="I1">
               <p>Departments of Anaesthesia and Cardiac Surgery, Sussex Cardiac Centre, Brighton, UK</p>
            </ins>
         </insg>
         <source>Critical Care</source>
         <supplement>
            <title>
               <p>18th Autumn Meeting of the Association of Cardiothoracic Anaesthetists</p>
            </title>
            <note>Meeting abstracts</note>
         </supplement>
         <conference>
            <title>
               <p>18th Autumn Meeting of the Association of Cardiothoracic Anaesthetists</p>
            </title>
            <location>London, UK</location>
            <date-range>16 November 2001</date-range>
         </conference>
         <issn>1364-8535</issn>
         <pubdate>2001</pubdate>
         <volume>5</volume>
         <issue>Suppl 4</issue>
         <fpage>8</fpage>
         <xrefbib>
            <pubid idtype="doi">10.1186/cc1440</pubid>
         </xrefbib>
      </bibl>
      <history>
         <pub>
            <date>
               <day>7</day>
               <month>11</month>
               <year>2001</year>
            </date>
         </pub>
      </history>
      <cpyrt>
         <year>2001</year>
         <collab>BioMed Central Ltd</collab>
      </cpyrt>
   </fm>
   <meta>
      <classifications>
         <classification type="BMC" subtype="old_arx_id">cc-5-s4-8</classification>
      </classifications>
   </meta>
   <bdy>
      <sec>
         <st>
            <p>Objective</p>
         </st>
         <p>Acute haemodynamic changes occur frequently during off-pump coronary artery surgery (OPCAB). Currently used haemodynamic monitors are not satisfactory during this procedure. We assessed the feasibility of oesophageal Doppler insonation of the descending aorta to measure cardiac output and other haemodynamic indices continuously during OPCAB.</p>
      </sec>
      <sec>
         <st>
            <p>Methods</p>
         </st>
         <p>Twenty-five consecutive patients scheduled to undergo OPCAB were studied prospectively. The ethical committee waived the need for informed consent because the oesophageal Doppler monitor (CardioQ, Deltex, UK) was already in routine use in our hospital. Haemodynamic parameters were recorded at multiple intervals after anaesthetic induction; before sternotomy; before, during and after each anastomosis and at the end of surgery. Stroke volume, cardiac output (CO), corrected flow time (FTc), peak velocity(PV) and mean acceleration were measured or calculated by the Doppler monitor. Mean arterial pressure (MAP) and central venous pressure(CVP) were measured from radial artery and internal jugular venous cannulae respectively.</p>
      </sec>
      <sec>
         <st>
            <p>Results</p>
         </st>
         <p>Satisfactory Doppler signals were not obtained in one patient. Two patients were converted to standard revascularisation using cardiopulmonary bypass because of technical considerations. One, 7 and 14 patients had one, two and three vessels grafted respectively. The haemodynamic data on these 22 patients are presented in Table <tblr tid="T1">1</tblr> as mean and standard deviation.</p>
         <tbl id="T1">
            <title>
               <p>Table 1</p>
            </title>
            <caption>
               <p/>
            </caption>
            <tblbdy cols="6">
               <r>
                  <c>
                     <p/>
                  </c>
                  <c ca="center">
                     <p>CO (l/min)</p>
                  </c>
                  <c ca="center">
                     <p>MAP (mmHg)</p>
                  </c>
                  <c ca="center">
                     <p>CVP(mmHg)</p>
                  </c>
                  <c ca="center">
                     <p>FTc (s)</p>
                  </c>
                  <c ca="center">
                     <p>PV(cm/s)</p>
                  </c>
               </r>
               <r>
                  <c cspan="6">
                     <hr/>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Post Induction</p>
                  </c>
                  <c ca="center">
                     <p>4.28 &#177; 1.30</p>
                  </c>
                  <c ca="center">
                     <p>78 &#177; 21</p>
                  </c>
                  <c>
                     <p/>
                  </c>
                  <c ca="center">
                     <p>325 &#177; 44</p>
                  </c>
                  <c ca="center">
                     <p>50 &#177; 12</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Pre LAD</p>
                  </c>
                  <c ca="center">
                     <p>5.12 &#177; 1.41</p>
                  </c>
                  <c ca="center">
                     <p>72 &#177; 17</p>
                  </c>
                  <c ca="center">
                     <p>8 &#177; 4</p>
                  </c>
                  <c ca="center">
                     <p>355 &#177; 29</p>
                  </c>
                  <c ca="center">
                     <p>54 &#177; 17</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>During LAD</p>
                  </c>
                  <c ca="center">
                     <p>4.76 &#177; 1.26</p>
                  </c>
                  <c ca="center">
                     <p>68 &#177; 13</p>
                  </c>
                  <c ca="center">
                     <p>10 &#177; 4</p>
                  </c>
                  <c ca="center">
                     <p>353 &#177; 45</p>
                  </c>
                  <c ca="center">
                     <p>53 &#177; 16</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Post LAD</p>
                  </c>
                  <c ca="center">
                     <p>5.57 &#177; 1.68</p>
                  </c>
                  <c ca="center">
                     <p>71 &#177; 15</p>
                  </c>
                  <c ca="center">
                     <p>9 &#177; 5</p>
                  </c>
                  <c ca="center">
                     <p>359 &#177; 45</p>
                  </c>
                  <c ca="center">
                     <p>55 &#177; 16</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Pre Cx</p>
                  </c>
                  <c ca="center">
                     <p>5.46 &#177; 1.84</p>
                  </c>
                  <c ca="center">
                     <p>67 &#177; 12</p>
                  </c>
                  <c ca="center">
                     <p>13 &#177; 5</p>
                  </c>
                  <c ca="center">
                     <p>353 &#177; 60</p>
                  </c>
                  <c ca="center">
                     <p>53 &#177; 17</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>During Cx</p>
                  </c>
                  <c ca="center">
                     <p>4.19 &#177; 1.12</p>
                  </c>
                  <c ca="center">
                     <p>68 &#177; 10</p>
                  </c>
                  <c ca="center">
                     <p>16 &#177; 5</p>
                  </c>
                  <c ca="center">
                     <p>343 &#177; 50</p>
                  </c>
                  <c ca="center">
                     <p>48 &#177; 12</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Post Cx</p>
                  </c>
                  <c ca="center">
                     <p>5.67 &#177; 1.69</p>
                  </c>
                  <c ca="center">
                     <p>70 &#177; 13</p>
                  </c>
                  <c ca="center">
                     <p>7 &#177; 4</p>
                  </c>
                  <c ca="center">
                     <p>375 &#177; 56</p>
                  </c>
                  <c ca="center">
                     <p>57 &#177; 13</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Pre PDA</p>
                  </c>
                  <c ca="center">
                     <p>5.38 &#177; 1.39</p>
                  </c>
                  <c ca="center">
                     <p>83 &#177; 17</p>
                  </c>
                  <c ca="center">
                     <p>12 &#177; 4</p>
                  </c>
                  <c ca="center">
                     <p>375 &#177; 42</p>
                  </c>
                  <c ca="center">
                     <p>52 &#177; 17</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>During PDA</p>
                  </c>
                  <c ca="center">
                     <p>5.38 &#177; 1.15</p>
                  </c>
                  <c ca="center">
                     <p>73 &#177; 13</p>
                  </c>
                  <c ca="center">
                     <p>14 &#177; 3</p>
                  </c>
                  <c ca="center">
                     <p>355 &#177; 61</p>
                  </c>
                  <c ca="center">
                     <p>54 &#177; 16</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Post PDA</p>
                  </c>
                  <c ca="center">
                     <p>5.14 &#177; 1.19</p>
                  </c>
                  <c ca="center">
                     <p>68 &#177; 13</p>
                  </c>
                  <c ca="center">
                     <p>9 &#177; 4</p>
                  </c>
                  <c ca="center">
                     <p>356 &#177; 39</p>
                  </c>
                  <c ca="center">
                     <p>53 &#177; 16</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Chest closed</p>
                  </c>
                  <c ca="center">
                     <p>4.89 &#177; 1.34</p>
                  </c>
                  <c ca="center">
                     <p>67 &#177; 12</p>
                  </c>
                  <c ca="center">
                     <p>9 &#177; 3</p>
                  </c>
                  <c ca="center">
                     <p>338 &#177; 40</p>
                  </c>
                  <c ca="center">
                     <p>57 &#177; 15</p>
                  </c>
               </r>
            </tblbdy>
            <tblfn>
               <p>LAD (left anterior descending artery) = 21 patients, Cx (circumflex artery) = 18 patients, PDA (posterior descending artery) = 15 patients. Pre, during and post refer to immediately before, during and after anastomosis.</p>
            </tblfn>
         </tbl>
      </sec>
      <sec>
         <st>
            <p>Conclusion</p>
         </st>
         <p>The oesophageal Doppler was able to monitor cardiac output and other haemodynamic parameters continuously throughout OPCAB. Further studies are needed to determine whether or not active haemodynamic management assisted by oesophageal Doppler monitoring during OPCAB improves patient outcome.</p>
      </sec>
   </bdy>
</art>
