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<art>
   <ui>cc1805</ui>
   <ji>CCJ</ji>
   <fm>
      <dochead>Meeting abstract</dochead>
      <bibl>
         <title>
            <p>A survey of non-depolarising muscle relaxants used in cardiac anaesthesia and surgery</p>
         </title>
         <aug>
            <au id="A1">
               <snm>Briggs</snm>
               <fnm>S</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A2">
               <snm>Thomas</snm>
               <fnm>R</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A3">
               <snm>Goodyear</snm>
               <fnm>P</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A4">
               <snm>Smith</snm>
               <fnm>D</fnm>
               <insr iid="I1"/>
            </au>
         </aug>
         <insg>
            <ins id="I1">
               <p>Department of Anaesthesia, Southampton University Hospitals NHS Trust, Tremona Road, Southampton SO16 6YD, UK</p>
            </ins>
         </insg>
         <source>Critical Care</source>
         <supplement>
            <title>
               <p>19th Spring Meeting of the Association of Cardiothoracic Anaesthetists</p>
            </title>
            <sponsor>
               <note>Supported by an unrestricted educational grant from Bayer plc</note>
            </sponsor>
            <note>Meeting abstracts</note>
         </supplement>
         <conference>
            <title>
               <p>19th Spring Meeting of the Association of Cardiothoracic Anaesthetists</p>
            </title>
            <location>Cambridge, UK</location>
            <date-range>21 June 2002</date-range>
         </conference>
         <issn>1364-8535</issn>
         <pubdate>2002</pubdate>
         <volume>6</volume>
         <issue>Suppl 2</issue>
         <fpage>1</fpage>
         <xrefbib>
            <pubidlist>
               <pubid idtype="pmpid">15743461</pubid>
               <pubid idtype="doi">10.1186/cc1805</pubid>
            </pubidlist>
         </xrefbib>
      </bibl>
      <history>
         <pub>
            <date>
               <day>9</day>
               <month>7</month>
               <year>2002</year>
            </date>
         </pub>
      </history>
   </fm>
   <meta>
      <classifications>
         <classification type="BMC" subtype="old_arx_id">cc-6-s2-1</classification>
      </classifications>
   </meta>
   <bdy>
      <sec>
         <st>
            <p>Introduction</p>
         </st>
         <p>Residual neuromuscular blockade contributes to postoperative morbidity and mortality, and is more common with long-acting non-depolarising muscle relaxants (NDMRs) such as pancuronium [<abbr bid="B1">1</abbr>]. This phenomenon may be a common occurrence in 'fast-track' managed cardiac patients administered long-acting NDMRs. We examine the usage of NDMRs in cardiac anaesthesia in the United Kingdom.</p>
      </sec>
      <sec>
         <st>
            <p>Methods</p>
         </st>
         <p>A postal questionnaire was sent to 310 consultant cardiac anaesthetists in the United Kingdom. We asked which NDMRs are preferred (differentiating between 'fast-track' [FT] and 'non-fast-track' [NFT] management of patients), and what methods are used to assess neuromuscular function prior to extubation.</p>
      </sec>
      <sec>
         <st>
            <p>Results</p>
         </st>
         <p>There was a 72.6% (225/310) response rate, of which 217 responses were valid. A single-agent NDMR technique is most prevalent for both NFT (92.2%) and FT patients (88.5%). Pancuronium (either as sole agent or in combination with another NDMR) was the first choice for NFT and FT patients, 73.7% and 52.1% respectively. For both management strategies, rocuronium is the next most popular agent. Benzylisoquinolinium derivatives are not in common usage. Forty-nine out of 211 anaesthetists (where a comparison could be made) changed their choice of NDMR between NFT and FT patients. The majority of these anaesthetists (85.7%) remove pancuronium from their practice for FT patients. Of respondents, 20.7% (45/217) indicated that an assessment of neuromuscular function was part of an extubation protocol; 75.6% (34/45) of these respondents detailed only clinical methods, whilst 6.7% (3/45) indicated use of a 'neuromuscular function monitor' alone, with 15.6% (7/45) indicating use of both methods. Amongst the responses indicating 'neuromuscular function monitor' methods, an assessment of the 'train-of-four' was the commonest response. Less than 10% monitor the neuromuscular junction during surgery.</p>
      </sec>
      <sec>
         <st>
            <p>Conclusions</p>
         </st>
         <p>Pancuronium remains the most popular NDMR for all types of cardiac anaesthesia. Some anaesthetists modify their choice of NDMR for FT management, changing from pancuronium to a shorter acting NDMR as the commonest adaptation. A minority of respondents indicated that a protocol exists to routinely assess the neuromuscular function prior to extubation.</p>
      </sec>
   </bdy>
   <bm>
      <refgrp>
         <bibl id="B1">
            <title>
               <p>Monitoring neuromuscular transmission.</p>
            </title>
            <aug>
               <au>
                  <snm>Torda</snm>
                  <fnm>TA</fnm>
               </au>
            </aug>
            <source>Anaesth Intensive Care</source>
            <pubdate>2002</pubdate>
            <volume>30</volume>
            <fpage>123</fpage>
            <lpage>133</lpage>
            <xrefbib>
               <pubid idtype="pmpid">12002918</pubid>
            </xrefbib>
         </bibl>
      </refgrp>
   </bm>
</art>
