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<art>
   <ui>cc3069</ui>
   <ji>CCJ</ji>
   <fm>
      <dochead>Poster presentation</dochead>
      <bibl>
         <title>
            <p>Clinical characteristics of ventilator-associated pneumonia patients and control patients</p>
         </title>
         <aug>
            <au id="A1">
               <snm>Moock</snm>
               <fnm>M</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A2">
               <snm>Maia</snm>
               <fnm>LL</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A3">
               <snm>Meserami</snm>
               <fnm>ALC</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A4">
               <snm>Broncher</snm>
               <fnm>CM</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A5">
               <snm>Oliveira</snm>
               <fnm>JL</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A6">
               <snm>Oliveira</snm>
               <fnm>SC</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A7">
               <snm>Orlando</snm>
               <fnm>JMO</fnm>
               <insr iid="I1"/>
            </au>
         </aug>
         <insg>
            <ins id="I1">
               <p>ICU Hospital Geral de Pedreira, S&#227;o Paulo, Brazil</p>
            </ins>
         </insg>
         <source>Critical Care</source>
         <supplement>
            <title>
               <p>25th International Symposium on Intensive Care and Emergency Medicine</p>
            </title>
            <note>Meeting abstracts</note>
         </supplement>
         <conference>
            <title>
               <p>25th International Symposium on Intensive Care and Emergency Medicine</p>
            </title>
            <location>Brussels, Belgium</location>
            <date-range>21&#8211;25 March 2005</date-range>
            <url>http://www.intensive.org/</url>
         </conference>
         <issn>1364-8535</issn>
         <pubdate>2005</pubdate>
         <volume>9</volume>
         <issue>Suppl 1</issue>
         <fpage>P6</fpage>
         <xrefbib>
            <pubid idtype="doi">10.1186/cc3069</pubid>
         </xrefbib>
      </bibl>
      <history>
         <pub>
            <date>
               <day>7</day>
               <month>3</month>
               <year>2005</year>
            </date>
         </pub>
      </history>
      <cpyrt>
         <year>2005</year>
         <collab>BioMed Central Ltd</collab>
      </cpyrt>
   </fm>
   <bdy>
      <sec>
         <st>
            <p>Introduction</p>
         </st>
         <p>Ventilator-associated pneumonia (VAP) represents 80% of all nosocomial pneumonia. The aim of this study is an epidemiological, performance and outcome evaluation of an ICU, focused in VAP.</p>
      </sec>
      <sec>
         <st>
            <p>Methods</p>
         </st>
         <p>The study was performed in a 13-bed ICU located in S&#227;o Paulo, Brazil, during 2003. It was a retrospective study, where all consecutive patients admitted were included. All data were collected and analysed in a Brazilian system of performance and quality in the ICU, called QuaTI<sup>&#174;</sup>. Statistical analyses were done, supported by the EpiInfo 2002 software. Clinical characteristics of all patients were presented and then two groups were analysed and compared: VAP group (<it>n </it>= 28) and control group (<it>n </it>= 231) composed of ventilated patients who did not develop VAP.</p>
      </sec>
      <sec>
         <st>
            <p>Results</p>
         </st>
         <p>From 11 January to 31 December, 483 patients were admitted; 55.69%, were male; median age was 59 years, 362 medical and 121 surgical patients; medium length of stay was 8.91 &#177; 13.07 days. APACHE II median score was 11.78 &#177; 7.13; mortality rate was 29.6% and standard mortality rate, calculated by APACHE II, was 1.01. The rate of ventilated patients was 259/483 (53.62%). The VAP incidence was 10.81% and the rate was 10.84 per 1000 ventilator days. The infection agent was identified in 15 patients by bronchoalveolar lavage or blood cultures. The more prevalent were <it>Pseudomonas aeuriginosa </it>(6/28), <it>Klebisiella pneumoniae </it>(2/28), <it>Staphylococcus aureus </it>(2/28).</p>
      </sec>
      <sec>
         <st>
            <p>Conclusions</p>
         </st>
         <p>VAP did not increase mortality but improved ventilated days, ICU length of stay and assistance costs. The APACHE II score was significantly higher in patients who developed VAP. <it>P. aeuriginosa </it>was the predominant pathogen.</p>
         <tbl id="T1">
            <title>
               <p>Table 1</p>
            </title>
            <tblbdy cols="4">
               <r>
                  <c ca="left">
                     <p>Characteristics</p>
                  </c>
                  <c ca="center">
                     <p>VAP (<it>n </it>= 28)</p>
                  </c>
                  <c ca="center">
                     <p>Controls (<it>n </it>= 231)</p>
                  </c>
                  <c ca="center">
                     <p><it>P </it>value</p>
                  </c>
               </r>
               <r>
                  <c cspan="4">
                     <hr/>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Age (years), median</p>
                  </c>
                  <c ca="center">
                     <p>57</p>
                  </c>
                  <c ca="center">
                     <p>66</p>
                  </c>
                  <c ca="center">
                     <p>0.10</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>% male</p>
                  </c>
                  <c ca="center">
                     <p>85.7</p>
                  </c>
                  <c ca="center">
                     <p>74</p>
                  </c>
                  <c ca="center">
                     <p>0.17</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Medical</p>
                  </c>
                  <c ca="center">
                     <p>24</p>
                  </c>
                  <c ca="center">
                     <p>171</p>
                  </c>
                  <c ca="center">
                     <p>0.17</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Surgical</p>
                  </c>
                  <c ca="center">
                     <p>4</p>
                  </c>
                  <c ca="center">
                     <p>60</p>
                  </c>
                  <c ca="center">
                     <p>0.17</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>ICU stay (days)</p>
                  </c>
                  <c ca="center">
                     <p>30.79 &#177; 18.06</p>
                  </c>
                  <c ca="center">
                     <p>12.25 &#177; 14.97</p>
                  </c>
                  <c ca="center">
                     <p>0.000</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Ventilation days</p>
                  </c>
                  <c ca="center">
                     <p>27.61 &#177; 20.19</p>
                  </c>
                  <c ca="center">
                     <p>10.41 &#177; 13.21</p>
                  </c>
                  <c ca="center">
                     <p>0.000</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>APACHE II score</p>
                  </c>
                  <c ca="center">
                     <p>16.50 &#177; 5.77</p>
                  </c>
                  <c ca="center">
                     <p>13.96 &#177; 7.39</p>
                  </c>
                  <c ca="center">
                     <p>0.04</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Death risk (%)</p>
                  </c>
                  <c ca="center">
                     <p>21.39</p>
                  </c>
                  <c ca="center">
                     <p>33.32</p>
                  </c>
                  <c ca="center">
                     <p>0.02</p>
                  </c>
               </r>
               <r>
                  <c ca="left">
                     <p>Mortality rate (%)</p>
                  </c>
                  <c ca="center">
                     <p>32.14</p>
                  </c>
                  <c ca="center">
                     <p>51.52</p>
                  </c>
                  <c ca="center">
                     <p>0.053</p>
                  </c>
               </r>
            </tblbdy>
         </tbl>
      </sec>
   </bdy>
   <bm>
      <refgrp>
         <bibl id="B1">
            <aug>
               <au>
                  <snm>Rello</snm>
                  <fnm>J</fnm>
               </au>
            </aug>
            <source>Crit Care Med</source>
            <pubdate>2003</pubdate>
            <volume>31</volume>
            <fpage>2544</fpage>
            <lpage>2551</lpage>
            <xrefbib>
               <pubidlist>
                  <pubid idtype="doi">10.1097/01.CCM.0000089928.84326.D2</pubid>
                  <pubid idtype="pmpid" link="fulltext">14530765</pubid>
               </pubidlist>
            </xrefbib>
         </bibl>
      </refgrp>
   </bm>
</art>
