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		Research Early versus late parenteral nutrition in ICU patients: cost analysis of the EPaNIC trial Simon Vanderheyden, Michael P Casaer, Katrien Kesteloot, Steven Simoens, Thomas De Rijdt, Guido Peers, Pieter J Wouters, Jocelijn Coenegrachts, Tine Grieten, Katleen Polders, Ann Maes, Alexander Wilmer, Jasperina Dubois, Greet Van den Berghe, Dieter Mesotten Critical Care 2012, 16:R96 (25 May 2012) Abstract \| Provisional PDF
		Research Blood transfusions increase circulating plasma free hemoglobin levels and plasma nitric oxide consumption: a prospective observational pilot study Iris C Vermeulen Windsant, Norbert CJ Wit, de, Jonas TC Sertorio, Erik AM Beckers, Jose E Tanus Santos, Michael J Jacobs, Wim A Buurman Critical Care 2012, 16:R95 (25 May 2012) Abstract \| Provisional PDF
		Research Assessment of hemodynamic efficacy and safety of 6% hydroxyethylstarch 130/0.4 versus 0.9% NaCl fluid replacement in patients with severe sepsis: The CRYSTMAS study Bertrand Guidet, Olivier Martinet, Thierry Boulain, Francois Philippart, Jean Francois Poussel, Julien Maizel, Xavier Forceville, Marc Feissel, Michel Hasselmann, Alexandra Heininger, Hugo Van Aken Critical Care 2012, 16:R94 (24 May 2012) Abstract \| Provisional PDF
		Research Implications of endotracheal tube biofilm in ventilator-associated pneumonia response: a state of concept Sara Gil-Perotin, Paula Ramirez, Veronica Marti, Jose Miguel Sahuquillo, Eva Gonzalez, Isabel Calleja, Rosario Menendez, Juan Bonastre Critical Care 2012, 16:R93 (23 May 2012) Abstract \| Provisional PDF
		Commentary Effects of non-neurological complications on traumatic brain injury outcome Kimberly S Meyer, Maxwell Boakye, Donald W Marion Critical Care 2012, 16:128 (23 May 2012) Abstract \| Full text \| PDF
		Commentary Contrast-induced nephropathy: attributable incidence and potential harm Lilian Pires de Freitas do Carmo, Etienne Macedo Critical Care 2012, 16:127 (23 May 2012) Abstract \| Full text \| PDF
		Research Association of gender with outcomes in critically ill patients Kamran Mahmood, Kamal Eldeirawi, Momen M Wahidi Critical Care 2012, 16:R92 (22 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Plasma sRAGE enables prediction of acute lung injury following cardiac surgery in children XiWang Liu, QiXing Chen, ShanShan Shi, Zhuo Shi, Ru Lin, LinHua Tan, JianGen Yu, Qiang Shu, XiangMing Fang Critical Care 2012, 16:R91 (22 May 2012) Abstract \| Provisional PDF \| PubMed
		Journal club critique New strategies to manage complicated pleural effusions Majed Safiyeh, David Huang Critical Care 2012, 16:312 (22 May 2012) Abstract \| Full text \| PDF
		Research Elevated plasma levels of heparin-binding protein in intensive care unit patients with severe sepsis and septic shock Adam Linder, Per Akesson, Malin Inghammar, Carl-Johan Treutiger, Anna Linner, Jonas Sunden-Cullberg Critical Care 2012, 16:R90 (21 May 2012) Abstract \| Provisional PDF \| PubMed
		Letter ROTEM®-guided coagulation factor concentrate therapy in trauma: 2-year experience in Venice, Italy Alberto Grassetto, Marco De Nardin, Bernadetta Ganzerla, Monica Geremia, Debora Saggioro, Elena Serafini, Silvia Zampieri, Manuela Toffoli, Daniele Penzo, Antonio Bossi, Carlo Maggiolo Critical Care 2012, 16:428 (21 May 2012) Abstract \| Full text \| PDF
		Research Red cell distribution width improves the simplified acute physiology score for risk prediction in unselected critically ill patients Sabina Hunziker, Leo A Celi, Joon Lee, Michael D Howell Critical Care 2012, 16:R89 (18 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Combining intermediate levels of the endotoxin activity assay (EAA) with other biomarkers in the assessment of patients with sepsis: results of an observational study Arino Yaguchi, Junji Yuzawa, David J Klein, Munekazu Takeda, Tomoyuki Harada Critical Care 2012, 16:R88 (18 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Multiple injuries after earthquakes: a retrospective analysis on 1871 injured patients from the 2008 Wenchuan earthquake Zhao Lu-Ping, Jose M Rodriguez-Llanes, Wu Qi, Barbara van den Oever, Lina Westman, Manuel Albela, Pan Liang, Chen Gao, Zhang De-Sheng, Melany Hughes, Johan von Schreeb, Debarati Guha-Sapir Critical Care 2012, 16:R87 (17 May 2012) Abstract \| Provisional PDF \| PubMed
		Commentary Apolipoprotein M - a new biomarker in sepsis Christina Christoffersen, Lars Nielsen Critical Care 2012, 16:126 (17 May 2012) Abstract \| Full text \| PDF \| PubMed
		Research The intravascular volume effect of ringer's lactate is below 20%: a prospective study in humans Matthias Jacob, Daniel Chappell, Klaus Hofmann-Kiefer, Tobias Helfen, Anna Schuelke, Barbara Jacob, Alexander Burges, Peter Conzen, Markus Rehm Critical Care 2012, 16:R86 (16 May 2012) Abstract \| Provisional PDF \| PubMed
		Research A pilot prospective study on closed loop controlled ventilation and oxygenation in ventilated children during the weaning phase Philippe Jouvet, Allen Eddington, Valerie Payen, Alice Bourdessoule, Guillaume Emeriaud, Ricardo Lopez Gasco, Marc Wysocki Critical Care 2012, 16:R85 (16 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Antipsychotic use and diagnosis of delirium in the intensive care unit Joshua T Swan, Kalliopi Fitousis, Jeffrey B Hall, S ROB Todd, Krista L Turner Critical Care 2012, 16:R84 (16 May 2012) Abstract \| Provisional PDF \| PubMed
		Book report Neurology Emergencies Rajat Dhar, Michael Diringer Critical Care 2012, 16:311 (16 May 2012) Abstract \| Full text \| PDF
		Research Early course of microcirculatory perfusion in eye and digestive tract during hypodynamic sepsis Andrius Pranskunas, Vidas Pilvinis, Zilvinas Dambrauskas, Renata Rasimaviciute, Rita Planciuniene, Paulius Dobozinskas, Vincentas Veikutis, Dinas Vaitkaitis, E Christiaan Boerma Critical Care 2012, 16:R83 (15 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Evaluation of a new pocket echoscopic device for focused-cardiac ultrasonography in emergency setting Matthieu Biais, Cedric Carrie, Francois Delaunay, Nicolas Morel, Philippe Revel, Gerard Janvier Critical Care 2012, 16:R82 (14 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Transthoracic Echocardiography with Doppler Tissue Imaging predicts weaning failure from mechanical ventilation: evolution of the left ventricle relaxation rate during a spontaneous breathing trial is the key factor in weaning outcome Sebastien Moschietto, Denis Doyen, Ludovic Grech, Jean Dellamonica, Herve Hyvernat, Gilles Bernardin Critical Care 2012, 16:R81 (14 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Gender differences in psychological morbidity and treatment in intensive care survivors - a cohort study Anna Schandl, Matteo Bottai, Elisabeth Hellgren, Örjan Sundin, Peter Sackey Critical Care 2012, 16:R80 (14 May 2012) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Depression and post-traumatic stress are more common in women than men after critical illness, indicating the need for psychological and physical 'follow-up' to reduce the incidence of these symptoms.
		Commentary Insulin therapy improves protein metabolism in the critically ill Elena Bogdanovic, Marc G Jeschke Critical Care 2012, 16:125 (14 May 2012) Abstract \| Full text \| PDF \| PubMed
		Research Comparison of accuracy of optic nerve ultrasound for the detection of intracranial hypertension in the setting of acutely fluctuating vs stable ICP: post-hoc analysis of data from a prospective, blinded single center study Venkatakrishna Rajajee, Jeffrey J Fletcher, Lauryn R Rochlen, Teresa L Jacobs Critical Care 2012, 16:R79 (11 May 2012) Abstract \| Provisional PDF \| PubMed

	All
		Research Early versus late parenteral nutrition in ICU patients: cost analysis of the EPaNIC trial Simon Vanderheyden, Michael P Casaer, Katrien Kesteloot, Steven Simoens, Thomas De Rijdt, Guido Peers, Pieter J Wouters, Jocelijn Coenegrachts, Tine Grieten, Katleen Polders, Ann Maes, Alexander Wilmer, Jasperina Dubois, Greet Van den Berghe, Dieter Mesotten Critical Care 2012, 16:R96 (25 May 2012) Abstract \| Provisional PDF
		Research Blood transfusions increase circulating plasma free hemoglobin levels and plasma nitric oxide consumption: a prospective observational pilot study Iris C Vermeulen Windsant, Norbert CJ Wit, de, Jonas TC Sertorio, Erik AM Beckers, Jose E Tanus Santos, Michael J Jacobs, Wim A Buurman Critical Care 2012, 16:R95 (25 May 2012) Abstract \| Provisional PDF
		Research Assessment of hemodynamic efficacy and safety of 6% hydroxyethylstarch 130/0.4 versus 0.9% NaCl fluid replacement in patients with severe sepsis: The CRYSTMAS study Bertrand Guidet, Olivier Martinet, Thierry Boulain, Francois Philippart, Jean Francois Poussel, Julien Maizel, Xavier Forceville, Marc Feissel, Michel Hasselmann, Alexandra Heininger, Hugo Van Aken Critical Care 2012, 16:R94 (24 May 2012) Abstract \| Provisional PDF
		Research Implications of endotracheal tube biofilm in ventilator-associated pneumonia response: a state of concept Sara Gil-Perotin, Paula Ramirez, Veronica Marti, Jose Miguel Sahuquillo, Eva Gonzalez, Isabel Calleja, Rosario Menendez, Juan Bonastre Critical Care 2012, 16:R93 (23 May 2012) Abstract \| Provisional PDF
		Commentary Effects of non-neurological complications on traumatic brain injury outcome Kimberly S Meyer, Maxwell Boakye, Donald W Marion Critical Care 2012, 16:128 (23 May 2012) Abstract \| Full text \| PDF
		Commentary Contrast-induced nephropathy: attributable incidence and potential harm Lilian Pires de Freitas do Carmo, Etienne Macedo Critical Care 2012, 16:127 (23 May 2012) Abstract \| Full text \| PDF
		Research Association of gender with outcomes in critically ill patients Kamran Mahmood, Kamal Eldeirawi, Momen M Wahidi Critical Care 2012, 16:R92 (22 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Plasma sRAGE enables prediction of acute lung injury following cardiac surgery in children XiWang Liu, QiXing Chen, ShanShan Shi, Zhuo Shi, Ru Lin, LinHua Tan, JianGen Yu, Qiang Shu, XiangMing Fang Critical Care 2012, 16:R91 (22 May 2012) Abstract \| Provisional PDF \| PubMed
		Journal club critique New strategies to manage complicated pleural effusions Majed Safiyeh, David Huang Critical Care 2012, 16:312 (22 May 2012) Abstract \| Full text \| PDF
		Research Elevated plasma levels of heparin-binding protein in intensive care unit patients with severe sepsis and septic shock Adam Linder, Per Akesson, Malin Inghammar, Carl-Johan Treutiger, Anna Linner, Jonas Sunden-Cullberg Critical Care 2012, 16:R90 (21 May 2012) Abstract \| Provisional PDF \| PubMed
		Letter ROTEM®-guided coagulation factor concentrate therapy in trauma: 2-year experience in Venice, Italy Alberto Grassetto, Marco De Nardin, Bernadetta Ganzerla, Monica Geremia, Debora Saggioro, Elena Serafini, Silvia Zampieri, Manuela Toffoli, Daniele Penzo, Antonio Bossi, Carlo Maggiolo Critical Care 2012, 16:428 (21 May 2012) Abstract \| Full text \| PDF
		Research Red cell distribution width improves the simplified acute physiology score for risk prediction in unselected critically ill patients Sabina Hunziker, Leo A Celi, Joon Lee, Michael D Howell Critical Care 2012, 16:R89 (18 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Combining intermediate levels of the endotoxin activity assay (EAA) with other biomarkers in the assessment of patients with sepsis: results of an observational study Arino Yaguchi, Junji Yuzawa, David J Klein, Munekazu Takeda, Tomoyuki Harada Critical Care 2012, 16:R88 (18 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Multiple injuries after earthquakes: a retrospective analysis on 1871 injured patients from the 2008 Wenchuan earthquake Zhao Lu-Ping, Jose M Rodriguez-Llanes, Wu Qi, Barbara van den Oever, Lina Westman, Manuel Albela, Pan Liang, Chen Gao, Zhang De-Sheng, Melany Hughes, Johan von Schreeb, Debarati Guha-Sapir Critical Care 2012, 16:R87 (17 May 2012) Abstract \| Provisional PDF \| PubMed
		Commentary Apolipoprotein M - a new biomarker in sepsis Christina Christoffersen, Lars Nielsen Critical Care 2012, 16:126 (17 May 2012) Abstract \| Full text \| PDF \| PubMed
		Research The intravascular volume effect of ringer's lactate is below 20%: a prospective study in humans Matthias Jacob, Daniel Chappell, Klaus Hofmann-Kiefer, Tobias Helfen, Anna Schuelke, Barbara Jacob, Alexander Burges, Peter Conzen, Markus Rehm Critical Care 2012, 16:R86 (16 May 2012) Abstract \| Provisional PDF \| PubMed
		Research A pilot prospective study on closed loop controlled ventilation and oxygenation in ventilated children during the weaning phase Philippe Jouvet, Allen Eddington, Valerie Payen, Alice Bourdessoule, Guillaume Emeriaud, Ricardo Lopez Gasco, Marc Wysocki Critical Care 2012, 16:R85 (16 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Antipsychotic use and diagnosis of delirium in the intensive care unit Joshua T Swan, Kalliopi Fitousis, Jeffrey B Hall, S ROB Todd, Krista L Turner Critical Care 2012, 16:R84 (16 May 2012) Abstract \| Provisional PDF \| PubMed
		Book report Neurology Emergencies Rajat Dhar, Michael Diringer Critical Care 2012, 16:311 (16 May 2012) Abstract \| Full text \| PDF
		Research Early course of microcirculatory perfusion in eye and digestive tract during hypodynamic sepsis Andrius Pranskunas, Vidas Pilvinis, Zilvinas Dambrauskas, Renata Rasimaviciute, Rita Planciuniene, Paulius Dobozinskas, Vincentas Veikutis, Dinas Vaitkaitis, E Christiaan Boerma Critical Care 2012, 16:R83 (15 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Evaluation of a new pocket echoscopic device for focused-cardiac ultrasonography in emergency setting Matthieu Biais, Cedric Carrie, Francois Delaunay, Nicolas Morel, Philippe Revel, Gerard Janvier Critical Care 2012, 16:R82 (14 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Transthoracic Echocardiography with Doppler Tissue Imaging predicts weaning failure from mechanical ventilation: evolution of the left ventricle relaxation rate during a spontaneous breathing trial is the key factor in weaning outcome Sebastien Moschietto, Denis Doyen, Ludovic Grech, Jean Dellamonica, Herve Hyvernat, Gilles Bernardin Critical Care 2012, 16:R81 (14 May 2012) Abstract \| Provisional PDF \| PubMed
		Research Gender differences in psychological morbidity and treatment in intensive care survivors - a cohort study Anna Schandl, Matteo Bottai, Elisabeth Hellgren, Örjan Sundin, Peter Sackey Critical Care 2012, 16:R80 (14 May 2012) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Depression and post-traumatic stress are more common in women than men after critical illness, indicating the need for psychological and physical 'follow-up' to reduce the incidence of these symptoms.
		Commentary Insulin therapy improves protein metabolism in the critically ill Elena Bogdanovic, Marc G Jeschke Critical Care 2012, 16:125 (14 May 2012) Abstract \| Full text \| PDF \| PubMed
		Research Comparison of accuracy of optic nerve ultrasound for the detection of intracranial hypertension in the setting of acutely fluctuating vs stable ICP: post-hoc analysis of data from a prospective, blinded single center study Venkatakrishna Rajajee, Jeffrey J Fletcher, Lauryn R Rochlen, Teresa L Jacobs Critical Care 2012, 16:R79 (11 May 2012) Abstract \| Provisional PDF \| PubMed