Latest articles

	Research     Enoxaparin - effective dosage for intensive care patients: double-blinded, randomised clinical trial Sian Robinson, Aleksander Zincuk, Thomas Strom, Torben Bjerregaard Larsen, Bjarne Rasmussen, Palle Toft Critical Care 2010, 14:R41 (18 March 2010) [Abstract] [Provisional PDF]
	Research     Resuscitation with low volume hydroxyethylstarch 130kDa/0.4 is not associated with acute kidney injury Nicolas Boussekey, Raphael Darmon, Joachim Langlois, Serge Alfandari, Patrick Devos, Agnes Meybeck, Arnaud Chiche, Hugues Georges, Olivier Leroy Critical Care 2010, 14:R40 (18 March 2010) [Abstract] [Provisional PDF]
	Research     Mechanical ventilation with high tidal volume induces inflammation in patients without lung disease Roselaine P Oliveira, Marcio P Hetzel, Mauro A Silva, Daniele Dallegrave, Gilberto Friedman Critical Care 2010, 14:R39 (18 March 2010) [Abstract] [Provisional PDF]
	Research     Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial Pratik P Pandharipande, Robert D Sanders, Timothy D Girard, Stuart McGrane, Jennifer L Thompson, Ayumi K Shintani, Daniel L Herr, Mervyn Maze, E Wesley Ely, The MENDS Investigators Critical Care 2010, 14:R38 (16 March 2010) [Abstract] [Provisional PDF] [PubMed] [Related articles]
	Research     Bedside adherence to clinical practice guidelines for enteral nutrition in critically ill patients receiving mechanical ventilation: a prospective, multi-centre, observational study Jean-Pierre Quenot, Gaetan Plantefeve, Jean-Luc Baudel, Isabelle Camilatto, Emmanuelle Bertholet, Romain Cailliod, Jean Reignier, Jean-Philippe Rigaud Critical Care 2010, 14:R37 (16 March 2010) [Abstract] [Provisional PDF] [PubMed] [Related articles]
	Research     Alveolar fluid clearance in healthy pigs and influence of positive end-expiratory pressure Manuel Garcia-Delgado, Angel Touma-Fernandez, Virginia Chamorro-Marin, Antonio Ruiz-Aguilar, Eduardo Aguilar-Alonso, Enrique Fernandez-Mondejar Critical Care 2010, 14:R36 (16 March 2010) [Abstract] [Provisional PDF] [PubMed] [Related articles]

Review 

Journal club critique   

• Oxygen consumption and lactic acidosis (Heikki Savolainen, 22Feb2010)
  Dear Editor, The interesting investigation shows that the biguanidine treatment interferes with the oxygen consumption (1). This is compatible with the fact that eg. metformin... [read full comment]
  Comment on: Protti A et al. Critical Care, 14:R22
• Amino acid imbalance and encephalopathy (Heikki Savolainen, 12Feb2010)
  Dear Editor, This investigations shows that infusion of LPS may alter the brain uptake of amino acids. It is thought that this may be a contributing factor to the clinical... [read full comment]
  Comment on: Berg RMG et al. Critical Care, 14:R16
• Vitamin D is also useful for septicemia (William B. Grant, 12Feb2010)
  This is a great paper. Related to their finding is that vitamin D reduces the risk of septis/septicemia, in part through induction of cathelicidin and defensins, which have... [read full comment]
  Comment on: Barbosa VM et al. Critical Care, 14:R5