Table 6

Intracranial hemorrhages classified according to type during infusion period, postinfusion period, and for the total 28 days after initiation of infusion in all clinical trials

Intracranial hemorrhage type
During infusion period
During postinfusion period
Total

Parenchymal1
14
6
20
Subarachnoid
1
1
2
Subdural
0
1
1
Other/undetermined
1
1
2
Stroke with hemorrhagic transformation
0
7
7
Total
16
16
32

A total of 2786 patients treated with drotrecogin alfa (activated) infusion were included in this analysis. 1Spontaneously occurring parenchymal hemorrhage.

Bernard et al. Critical Care 2003 7:155   doi:10.1186/cc2167