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1.

Research   Open Access Highly Accessed

The effect of earplugs during the night on the onset of delirium and sleep perception: a randomized controlled trial in intensive care patients

Bart Van Rompaey, Monique M Elseviers, Wim Van Drom, Veronique Fromont, Philippe G Jorens Critical Care 2012, 16:R73 (4 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment | F1000 Biology |  Editor’s summary

The use of earplugs in the ICU can lead to a better night's sleep for patients, lower the incidence of confusion, and delay the onset of cognitive disturbances.

2.

Research   Open Access Highly Accessed

Investigating risk factors for psychological morbidity three months after intensive care: a prospective cohort study

Dorothy M Wade, David C Howell, John A Weinman, Rebecca J Hardy, Michael G Mythen, Chris R Brewin, Susana Borja-Boluda, Claire F Matejowsky, Rosalind A Raine Critical Care 2012, 16:R192 (15 October 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Patients experiencing acute psychological reactions in the intensive care unit (ICU) were found to be at an increased risk of developing mental illness after recovery; suggesting interventions during treatment could reduce psychological morbidity in ICU survivors.

3.

Review   Free Highly Accessed

Clinical review: The hospital of the future - building intelligent environments to facilitate safe and effective acute care delivery

Brian W Pickering, John M Litell, Vitaly Herasevich, Ognjen Gajic Critical Care 2012, 16:220 (26 April 2012)

Abstract | Full text | PDF | PubMed

4.

Research   Open Access Highly Accessed

Intensive care diaries reduce new onset post traumatic stress disorder following critical illness: a randomised, controlled trial

Christina Jones, Carl Bäckman, Maurizia Capuzzo, Ingrid Egerod, Hans Flaatten, Cristina Granja, Christian Rylander, Richard D Griffiths, the RACHEL group Critical Care 2010, 14:R168 (15 September 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 |  Editor’s summary

Patients recovering from critical illness are at a much lower risk of developing post traumatic stress disorder if they keep a diary during their time in intensive care.

5.

Commentary   Free Highly Accessed

Pulse pressure variation: beyond the fluid management of patients with shock

Frédéric Michard, Marcel R Lopes, Jose-Otavio C Auler Critical Care 2007, 11:131 (17 May 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

6.

Review   Free Highly Accessed

Clinical review: Mechanical ventilation in severe asthma

David R Stather, Thomas E Stewart Critical Care 2005, 9:581-587 (8 September 2005)

Abstract | Full text | PDF | PubMed

7.

Review   Free Highly Accessed

Human albumin in the management of complications of liver cirrhosis

Mauro Bernardi, Caterina Maggioli, Giacomo Zaccherini Critical Care 2012, 16:211 (20 March 2012)

Abstract | Full text | PDF | PubMed

8.

Research   Open Access Highly Accessed

Hemoglobin levels and transfusions in neurocritically ill patients: a systematic review of comparative studies

Philippe Desjardins, Alexis F Turgeon, Marie-Hélène Tremblay, François Lauzier, Ryan Zarychanski, Amélie Boutin, Lynne Moore, Lauralyn A McIntyre, Shane W English, Andrea Rigamonti, Jacques Lacroix, Dean A Fergusson Critical Care 2012, 16:R54 (2 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

9.

Research   Open Access Highly Accessed

Probiotics' effects on the incidence of nosocomial pneumonia in critically ill patients: a systematic review and meta-analysis

Kai-xiong Liu, Ying-gang Zhu, Jing Zhang, Li-li Tao, Jae-Woo Lee, Xiao-dan Wang, Jie-ming Qu Critical Care 2012, 16:R109 (25 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

10.

Research   Open Access Highly Accessed

The confusion assessment method for the intensive care unit (CAM-ICU) and intensive care delirium screening checklist (ICDSC) for the diagnosis of delirium: a systematic review and meta-analysis of clinical studies

Dimitri Gusmao-Flores, Jorge Ibrain Figueira Salluh, Ricardo Chalhub, Lucas C Quarantini Critical Care 2012, 16:R115 (3 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

The confusion assessment method for the intensive care unit is an excellent diagnostic tool for delirium in critically ill ICU patients, suggests a systematic review and meta-analysis.

11.

Research   Open Access Highly Accessed

Management of bleeding and coagulopathy following major trauma: an updated European guideline

Donat R Spahn, Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Daniela Filipescu, Beverley J Hunt, Radko Komadina, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Jean-Louis Vincent, Rolf Rossaint Critical Care 2013, 17:R76 (19 April 2013)

Abstract | Provisional PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The Task Force for Advanced Bleeding Care in Trauma have updated their guidelines on the management of bleeding following traumatic injury, with new recommendations addressing changes made in clinical care.

12.

Research   Open Access Highly Accessed

Antibiotic prescription patterns in the empiric therapy of severe sepsis: combination of antimicrobials with different mechanisms of action reduces mortality

Ana Díaz-Martín, María Martínez-González, Ricard Ferrer, Carlos Ortiz-Leyba, Enrique Piacentini, Maria Lopez-Pueyo, Ignacio Martín-Loeches, Mitchell M Levy, Antoni Artigas, José Garnacho-Montero, for the Edusepsis Study Group Critical Care 2012, 16:R223 (18 November 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Combining antibiotics with different mechanisms of action (different-class combination therapy) is associated with decreased mortality in severe sepsis and septic shock.

13.

Review   Free Highly Accessed

Clinical review: The impact of noise on patients' sleep and the effectiveness of noise reduction strategies in intensive care units

Hui Xie, Jian Kang, Gary H Mills Critical Care 2009, 13:208 (9 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

14.

Research   Open Access Highly Accessed

Vasopressin and terlipressin in adult vasodilatory shock: a systematic review and meta-analysis of nine randomized controlled trials

Ary Serpa Neto, Antônio P Nassar, Sérgio O Cardoso, José A Manetta, Victor GM Pereira, Daniel C Espósito, Maria CT Damasceno, James A Russell Critical Care 2012, 16:R154 (14 August 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

15.

Review   Free Highly Accessed

Neurogenic pulmonary edema

Danielle L Davison, Megan Terek, Lakhmir S Chawla Critical Care 2012, 16:212 (20 March 2012)

Abstract | Full text | PDF | PubMed

16.

Review   Subscription Highly Accessed

Clinical review: Practical approach to hyponatraemia and hypernatraemia in critically ill patients

Christian Overgaard-Steensen, Troels Ring Critical Care 2012, 17:206 (27 February 2013)

Abstract | Full text | PDF

17.

Review   Free Highly Accessed

Bench-to-bedside review: Mobilizing patients in the intensive care unit – from pathophysiology to clinical trials

Alex D Truong, Eddy Fan, Roy G Brower, Dale M Needham Critical Care 2009, 13:216 (13 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

Research   Open Access Highly Accessed

Renaissance of base deficit for the initial assessment of trauma patients: a base deficit-based classification for hypovolemic shock developed on data from 16,305 patients derived from the TraumaRegister DGU®

Manuel Mutschler, Ulrike Nienaber, Thomas Brockamp, Arasch Wafaisade, Tobias Fabian, Thomas Paffrath, Bertil Bouillon, Marc Maegele, the TraumaRegister DGU Critical Care 2013, 17:R42 (6 March 2013)

Abstract | Full text | PDF | PubMed | 1 comment |  Editor’s summary

Base deficit (BD)-based shock classification better discriminates the need for early blood transfusion and mortality in severely injured patients than the current Advanced Trauma Life Support (ATLS) protocol.

19.

Research   Open Access Highly Accessed

Electrocardiographic changes in therapeutic hypothermia

Corina L Rolfast, Erik J Lust, Carel C de Cock Critical Care 2012, 16:R100 (6 June 2012)

Abstract | Full text | PDF | PubMed

20.

Review   Free

Pulse oximetry

Amal Jubran Critical Care 1999, 3:R11-R17 (18 May 1999)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

21.

Review   Free Highly Accessed

Clinical review: Post-extubation laryngeal edema and extubation failure in critically ill adult patients

Bastiaan HJ Wittekamp, Walther NKA van Mook, Dave HT Tjan, Jan Zwaveling, Dennis CJJ Bergmans Critical Care 2009, 13:233 (1 December 2009)

Abstract | Full text | PDF | PubMed

22.

Research   Open Access Highly Accessed

Noninvasive ventilation immediately after extubation improves weaning outcome after acute respiratory failure: a randomized controlled trial

Susana R Ornico, Suzana M Lobo, Helder S Sanches, Maristela Deberaldini, Luciane T Tófoli, Ana M Vidal, Guilherme P Schettino, Marcelo B Amato, Carlos R Carvalho, Carmen S Barbas Critical Care 2013, 17:R39 (4 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A randomized controlled trial shows that non-invasive ventilation applied immediately after extubation prevents re-intubation and decreases hospital mortality when compared to oxygen mask therapy.

23.

Review   Free Highly Accessed

Prevention of central venous catheter-related infection in the intensive care unit

Denis Frasca, Claire Dahyot-Fizelier, Olivier Mimoz Critical Care 2010, 14:212 (9 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

Research   Open Access Highly Accessed

Evaluation of a new pocket echoscopic device for focused cardiac ultrasonography in an emergency setting

Matthieu Biais, Cédric Carrié, François Delaunay, Nicolas Morel, Philippe Revel, Gérard Janvier Critical Care 2012, 16:R82 (14 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

25.

Review   Subscription Highly Accessed

Clinical review: Does it matter which hemodynamic monitoring system is used?

Davinder Ramsingh, Brenton Alexander, Maxime Cannesson Critical Care 2012, 17:208 (5 March 2013)

Abstract | Full text | PDF

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