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	1.	Research The effect of earplugs during the night on the onset of delirium and sleep perception: a randomized controlled trial in intensive care patients Bart Van Rompaey, Monique M Elseviers, Wim Van Drom, Veronique Fromont, Philippe G Jorens Critical Care 2012, 16:R73 (4 May 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The use of earplugs in the ICU can lead to a better night's sleep for patients, lower the incidence of confusion, and delay the onset of cognitive disturbances.
	2.	Research Recommended β-lactam regimens are inadequate in septic patients treated with continuous renal replacement therapy Lucie Seyler, Frédéric Cotton, Fabio Taccone, Daniel De Backer, Pascale Macours, Jean-Louis Vincent, Frédérique Jacobs Critical Care 2011, 15:R137 (6 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	3.	Review Weaning from mechanical ventilation Inmaculada Alía, Andrés Esteban Critical Care 2000, 4:72-80 (18 February 2000) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	4.	Research Enteral nutrition with eicosapentaenoic acid, γ-linolenic acid and antioxidants in the early treatment of sepsis: results from a multicenter, prospective, randomized, double-blinded, controlled study: the INTERSEPT Study Alessandro Pontes-Arruda, Laércia Martins, Samya de Lima, Alexandre Isola, Diogo Toledo, Ederlon Rezende, Marcelo Maia, Gisele Magnan, the Investigating Nutritional Therapy with EPA, GLA and Antioxidants Role in Sepsis Treatment (INTERSEPT) Study Group Critical Care 2011, 15:R144 (9 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	5.	Research Management of bleeding following major trauma: an updated European guideline Rolf Rossaint, Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Beverley J Hunt, Radko Komadina, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Philip F Stahel, Jean-Louis Vincent, Donat R Spahn Critical Care 2010, 14:R52 (6 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	6.	Review Clinical review: The impact of noise on patients' sleep and the effectiveness of noise reduction strategies in intensive care units Hui Xie, Jian Kang, Gary H Mills Critical Care 2009, 13:208 (9 March 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	7.	Review Prevention of central venous catheter-related infection in the intensive care unit Denis Frasca, Claire Dahyot-Fizelier, Olivier Mimoz Critical Care 2010, 14:212 (9 March 2010) Abstract \| Full text \| PDF \| PubMed
	8.	Research Remarkable changes in the choice of timing to discuss organ donation with the relatives of a patient: a study in 228 organ donations in 20 years Yorick J de Groot, Hester F Lingsma, Mathieu van der Jagt, Jan Bakker, Jan NM IJzermans, Erwin JO Kompanje Critical Care 2011, 15:R235 (7 October 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The time at which organ donation is discussed with relatives of patients with catastrophic brain injury in the Netherlands has changed over 20 years, maybe contributing to the high refusal rate.
	9.	Review Delirium in the intensive care unit Timothy D Girard, Pratik P Pandharipande, E Wesley Ely Critical Care 2008, 12(Suppl 3):S3 (14 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	10.	Research Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group Rinaldo Bellomo, Claudio Ronco, John A Kellum, Ravindra L Mehta, Paul Palevsky, the ADQI workgroup Critical Care 2004, 8:R204-R212 (24 May 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| F1000 Medicine \| F1000 Biology
	11.	Review Clinical review: High-frequency oscillatory ventilation in adults – a review of the literature and practical applications Frank V Ritacca, Thomas E Stewart Critical Care 2003, 7:385-390 (17 April 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	12.	Research Clinical effectiveness of fresh frozen plasma compared with fibrinogen concentrate: a systematic review Sibylle Kozek-Langenecker, Benny Sørensen, John R Hess, Donat R Spahn Critical Care 2011, 15:R239 (14 October 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	13.	Review Evaluating and monitoring analgesia and sedation in the intensive care unit Curtis N Sessler, Mary Jo Grap, Michael AE Ramsay Critical Care 2008, 12(Suppl 3):S2 (14 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	14.	Review Clinical review: Severe asthma Spyros Papiris, Anastasia Kotanidou, Katerina Malagari, Charis Roussos Critical Care 2002, 6:30-44 (22 November 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	15.	Research Effects of probiotics on serum levels of Th1/Th2 cytokine and clinical outcomes in severe traumatic brain-injured patients: a prospective randomized pilot study Min Tan, Jing-Ci Zhu, Jiang Du, Li-Mei Zhang, Hua-Hua Yin Critical Care 2011, 15:R290 (2 December 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology \| Editor’s summary Prophylactic administration of probiotics appears to promote a return to a more normal Th1/Th2 balance in patients with severe traumatic brain injury, which may contribute to a decreased nosocomial infection rate.
	16.	Viewpoint A critique of fluid bolus resuscitation in severe sepsis Andrew K Hilton, Rinaldo Bellomo Critical Care 2012, 16:302 (25 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	17.	Research Replacement of fentanyl infusion by enteral methadone decreases the weaning time from mechanical ventilation: a randomized controlled trial Raquel Wanzuita, Luiz F Poli-de-Figueiredo, Felipe Pfuetzenreiter, Alexandre Cavalcanti, Glauco Westphal Critical Care 2012, 16:R49 (15 March 2012) Abstract \| Full text \| PDF \| PubMed
	18.	Research Prevention of ventilator-associated pneumonia, mortality and all intensive care unit acquired infections by topically applied antimicrobial or antiseptic agents: a meta-analysis of randomized controlled trials in intensive care units Claudia Pileggi, Aida Bianco, Domenico Flotta, Carmelo GA Nobile, Maria Pavia Critical Care 2011, 15:R155 (24 June 2011) Abstract \| Full text \| PDF \| PubMed
	19.	Review 'Cooperative sedation': optimizing comfort while maximizing systemic and neurological function Haley Goodwin, John J Lewin, Marek A Mirski Critical Care 2012, 16:217 (20 March 2012) Abstract \| Full text \| PDF \| PubMed
	20.	Research Reduction in hospital-wide mortality after implementation of a rapidresponse team: a long-term cohort study Jeremy R Beitler, Nate Link, Douglas B Bails, Kelli Hurdle, David H Chong Critical Care 2011, 15:R269 (15 November 2011) Abstract \| Full text \| PDF \| PubMed
	21.	Research Soluble urokinase-type plasminogen activator receptor levels in patients with burn injuries and inhalation trauma requiring mechanical ventilation: an observational cohort study Yara Backes, Koenraad F van der Sluijs, Anita M Tuip de Boer, Jorrit Hofstra, Alexander PJ Vlaar, Rogier M Determann, Paul Knape, David P Mackie, Marcus J Schultz Critical Care 2011, 15:R270 (16 November 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Pulmonary levels of soluble urokinase-type plasminogen activator receptor (suPAR) may be useful for diagnosis of inhalation injury, while systemic suPAR levels may be prognostic for duration of mechanical ventilation and ICU-stay.
	22.	Review Clinical review: Canadian National Advisory Committee on Blood and Blood Products - Massive Transfusion Consensus Conference 2011: report of the panel Walter H Dzik, Morris A Blajchman, Dean Fergusson, Morad Hameed, Blair Henry, Andrew W Kirkpatrick, Teresa Korogyi, Sarvesh Logsetty, Robert C Skeate, Simon Stanworth, Charles MacAdams, Brian Muirhead Critical Care 2011, 15:242 (8 December 2011) Abstract \| Full text \| PDF \| PubMed
	23.	Review Clinical review: Critical illness polyneuropathy and myopathy Greet Hermans, Bernard De Jonghe, Frans Bruyninckx, Greet Berghe Critical Care 2008, 12:238 (25 November 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	24.	Review Clinical review: Checklists - translating evidence into practice Bradford D Winters, Ayse P Gurses, Harold Lehmann, J Bryan Sexton, Carlyle Rampersad, Peter J Pronovost Critical Care 2009, 13:210 (31 December 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	25.	Research CLUE: a randomized comparative effectiveness trial of IV nicardipine versus labetalol use in the emergency department W Peacock, Joseph Varon, Brigitte M Baumann, Pierre Borczuk, Chad M Cannon, Abhinav Chandra, David M Cline, Deborah Diercks, Brian Hiestand, A Hsu, Preeti Jois-Bilowich, Brian Kaminski, Philip Levy, Richard M Nowak, Jon W Schrock Critical Care 2011, 15:R157 (27 June 2011) Abstract \| Full text \| PDF \| PubMed