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	1. 8405 Accesses	Research Management of bleeding and coagulopathy following major trauma: an updated European guideline Donat R Spahn, Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Daniela Filipescu, Beverley J Hunt, Radko Komadina, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Jean-Louis Vincent, Rolf Rossaint Critical Care 2013, 17:R76 (19 April 2013) Abstract \| Provisional PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The Task Force for Advanced Bleeding Care in Trauma have updated their guidelines on the management of bleeding following traumatic injury, with new recommendations addressing changes made in clinical care.
	2. 2933 Accesses	Research Continuous on-line glucose measurement by microdialysis in a central vein. A pilot study Christina Blixt, Olav Rooyackers, Bengt Isaksson, Jan Wernerman Critical Care 2013, 17:R87 (11 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A potential new tool for intravascular continuous glucose monitoring in intensive care patients could prevent hypoglycaemia or high glucose variability.
	3. 2823 Accesses	Research Noninvasive ventilation immediately after extubation improves weaning outcome after acute respiratory failure: a randomized controlled trial Susana R Ornico, Suzana M Lobo, Helder S Sanches, Maristela Deberaldini, Luciane T Tófoli, Ana M Vidal, Guilherme P Schettino, Marcelo B Amato, Carlos R Carvalho, Carmen S Barbas Critical Care 2013, 17:R39 (4 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A randomized controlled trial shows that non-invasive ventilation applied immediately after extubation prevents re-intubation and decreases hospital mortality when compared to oxygen mask therapy.
	4. 2822 Accesses	Research Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group Rinaldo Bellomo, Claudio Ronco, John A Kellum, Ravindra L Mehta, Paul Palevsky, the ADQI workgroup Critical Care 2004, 8:R204-R212 (24 May 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| F1000
	5. 2812 Accesses	Review Clinical review: Does it matter which hemodynamic monitoring system is used? Davinder Ramsingh, Brenton Alexander, Maxime Cannesson Critical Care 2012, 17:208 (5 March 2013) Abstract \| Full text \| PDF
	6. 2543 Accesses	Research Renaissance of base deficit for the initial assessment of trauma patients: a base deficit-based classification for hypovolemic shock developed on data from 16,305 patients derived from the TraumaRegister DGU^® Manuel Mutschler, Ulrike Nienaber, Thomas Brockamp, Arasch Wafaisade, Tobias Fabian, Thomas Paffrath, Bertil Bouillon, Marc Maegele, the TraumaRegister DGU Critical Care 2013, 17:R42 (6 March 2013) Abstract \| Full text \| PDF \| PubMed \| 1 comment \| Editor’s summary Base deficit (BD)-based shock classification better discriminates the need for early blood transfusion and mortality in severely injured patients than the current Advanced Trauma Life Support (ATLS) protocol.
	7. 2435 Accesses	Research Meropenem and piperacillin/tazobactam prescribing in critically ill patients: does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used? Mieke Carlier, Sofie Carrette, Jason A Roberts, Veronique Stove, Alain G Verstraete, Eric Hoste, Johan Decruyenaere, Pieter Depuydt, Jeffrey Lipman, Steven C Wallis, Jan J De Waele Critical Care 2013, 17:R84 (3 May 2013) Abstract \| Provisional PDF \| PubMed
	8. 2390 Accesses	Research Sepsis biomarkers: a review Charalampos Pierrakos, Jean-Louis Vincent Critical Care 2010, 14:R15 (9 February 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	9. 2280 Accesses	Research Management of bleeding following major trauma: an updated European guideline Rolf Rossaint, Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Beverley J Hunt, Radko Komadina, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Philip F Stahel, Jean-Louis Vincent, Donat R Spahn Critical Care 2010, 14:R52 (6 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	10. 2238 Accesses	Research Changes in hospital mortality for United States intensive care unit admissions from 1988 to 2012 Jack E Zimmerman, Andrew A Kramer, William A Knaus Critical Care 2013, 17:R81 (27 April 2013) Abstract \| Provisional PDF \| PubMed
	11. 2189 Accesses	Commentary The STOP the Bleeding Campaign Rolf Rossaint, Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Daniela Filipescu, Beverley J Hunt, Radko Komadina, Marc Maegele, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Jean-Louis Vincent, Donat R Spahn, the STOP the Bleeding Campaign Critical Care 2013, 17:136 (26 April 2013) Abstract \| Full text \| PDF \| PubMed
	12. 1978 Accesses	Research Clinical characteristics, sepsis interventions and outcomes in the obese patients with septic shock: an international multicenter cohort study Yaseen M Arabi, Saqib I Dara, Hani M Tamim, Asgar H Rishu, Abderrezak Bouchama, Mohammad K Khedr, Daniel Feinstein, Joseph E Parrillo, Kenneth E Wood, Sean P Keenan, Sergio Zanotti, Greg Martinka, Aseem Kumar, Anand Kumar, The Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group Critical Care 2013, 17:R72 (17 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The obesity paradox (lower mortality in the obese) is observed in patients admitted to intensive care with septic shock in a large international retrospective cohort study.
	13. 1950 Accesses	Research The effects of the semirecumbent position on hemodynamic status in patients on invasive mechanical ventilation - prospective randomized multivariable analysis Ivan Gocze, Felix Strenge, Florian Zeman, Marcus Creutzenberg, Bernhard M Graf, Hans J Schlitt, Thomas Bein Critical Care 2013, 17:R80 (26 April 2013) Abstract \| Provisional PDF \| PubMed
	14. 1920 Accesses	Research Outcome of ICU patients with Clostridium difficile infection Jean-Ralph Zahar, Carole Schwebel, Christophe Adrie, Maité Garrouste-Orgeas, Adrien Français, Aurélien Vesin, Molière Nguile-Makao, Alexis Tabah, Kevin Laupland, Alban Le-Monnier, Jean-François Timsit, the OUTCOMEREA study group Critical Care 2012, 16:R215 (5 November 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	15. 1915 Accesses	Research Management of bleeding following major trauma: a European guideline Donat R Spahn, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Giovanni Gordini, Philip F Stahel, Beverley J Hunt, Radko Komadina, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Jean-Louis Vincent, Rolf Rossaint Critical Care 2007, 11:R17 (13 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary State-of-the-art guidelines developed by a multidisciplinary task force provide evidence-based recommendations on the acute management of bleeding trauma patients, which when implemented may lead to improved patient outcomes.
	16. 1889 Accesses	Review Clinical review: Helmet and non-invasive mechanical ventilation in critically ill patients Antonio M Esquinas Rodriguez, Peter J Papadakos, Michele Carron, Roberto Cosentini, Davide Chiumello Critical Care 2013, 17:223 (25 April 2013) Abstract \| Full text \| PDF \| PubMed
	17. 1879 Accesses	Research Decreasing severe pain and serious adverse events while moving intensive care unit patients: a prospective interventional study (the NURSE-DO project) Audrey de Jong, Nicolas Molinari, Sylvie de Lattre, Claudine Gniadek, Julie Carr, Mathieu Conseil, Marie-Pierre Susbielles, Boris Jung, Samir Jaber, Gérald Chanques Critical Care 2013, 17:R74 (18 April 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Implementing a quality improvement project for pain management in an intensive care unit (ICU) decreases severe pain and serious adverse events when moving and handling patients.
	18. 1885 Accesses	Research Differences in compliance with Surviving Sepsis Campaign recommendations according to hospital entrance time: day versus night Monica Almeida, Orquidea Ribeiro, Irene Aragao, Altamiro Costa-Pereira, Teresa Cardoso Critical Care 2013, 17:R79 (23 April 2013) Abstract \| Provisional PDF \| PubMed
	19. 1794 Accesses	Review Neurogenic pulmonary edema Danielle L Davison, Megan Terek, Lakhmir S Chawla Critical Care 2012, 16:212 (20 March 2012) Abstract \| Full text \| PDF \| PubMed
	20. 1587 Accesses	Research Balanced versus chloride-rich solutions for fluid resuscitation in brain-injured patients: a randomized double-blind pilot study Antoine Roquilly, Olivier Loutrel, Raphael Cinotti, Elise Rosenczweig, Laurent Flet, Pierre Joachim Mahe, Romain Dumont, Anne Marie Chupin, Catherine Peneaux, Corinne Lejus, Yvonnick Blanloeil, Christelle Volteau, Karim Asehnoune Critical Care 2013, 17:R77 (19 April 2013) Abstract \| Provisional PDF \| PubMed
	21. 1577 Accesses	Review Assessment of volume responsiveness during mechanical ventilation: recent advances Xavier Monnet, Jean-Louis Teboul Critical Care 2013, 17:217 (19 March 2013) Abstract \| Full text \| PDF \| PubMed
	22. 1549 Accesses	Journal club critique Hydroxyethyl starch in severe sepsis: end of starch era? Carlos A Estrada, Raghavan Murugan Critical Care 2013, 17:310 (13 March 2013) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	23. 1534 Accesses	Commentary Sex and severe sepsis Bertrand Guidet, Eric Maury Critical Care 2013, 17:144 (15 May 2013) Abstract \| Full text \| PDF \| PubMed
	24. 1524 Accesses	Viewpoint The potential harm of oxygen therapy in medical emergencies Alexander D Cornet, Albertus J Kooter, Mike JL Peters, Yvo M Smulders Critical Care 2013, 17:313 (18 April 2013) Abstract \| Full text \| PDF \| PubMed
	25. 1517 Accesses	Letter Algorithm-based management of bleeding in patients with extracorporeal membrane oxygenation David Faraoni, Jerrold H Levy Critical Care 2013, 17:432 (8 May 2013) Abstract \| Full text \| PDF \| PubMed