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1: Lancet. 1977 Feb 26;1(8009):466-9.
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Incidence and severity of anaphylactoid reactions to colloid volume substitutes.

Ring J, Messmer K.

All available colloid volume substitutes carry the risk of anaphylactoid reactions. In a multicentre prospective trial, 69 cases of anaphylactoid reactions have been observed among 200 906 infusions of colloid volume substitutes. The frequency of severe reactions (shock, cardiac and/or respiratory arrest) was 0-003% for plasma-protein solutions, 0-006% for hydroxyethyl starch, 0-008% for dextran, and 0-038% for gelatin solutions.

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PMID: 65572 [PubMed - indexed for MEDLINE]