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Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis.

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ENHANCE: results of a global open-label trial of drotrecogin alfa (activated) in children with severe sepsis.

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The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis.

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International INtegrated Database for the Evaluation of severe sePsis and drotrecogin alfa (activated) THerapy: component trials and statistical methods for INDEPTH.

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Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated).

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Use of an integrated clinical trial database to evaluate the effect of timing of drotrecogin alfa (activated) treatment in severe sepsis.

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Clinical effectiveness and cost-effectiveness of drotrecogin alfa (activated) (Xigris) for the treatment of severe sepsis in adults: a systematic review and economic evaluation.

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From bench to bedside: a review of the clinical trial development plan of drotrecogin alfa (activated).

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Timing of drotrecogin alfa (activated) initiation in treatment of severe sepsis: a database cohort study of hospital mortality, length of stay, and costs.

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A registry of patients treated with drotrecogin alfa (activated) in Belgian intensive care units--an observational study.

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Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis.

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