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1:

The microcirculation is the motor of sepsis.

Ince C.

Crit Care. 2005;9 Suppl 4:S13-9. Epub 2005 Aug 25. Review.

PMID: 16168069 [PubMed - indexed for MEDLINE]

2:

Microcirculatory recruitment maneuvers correct tissue CO2 abnormalities in sepsis.

Almac E, Siegemund M, Demirci C, Ince C.

Minerva Anestesiol. 2006 Jun;72(6):507-19. Review.

PMID: 16682924 [PubMed - indexed for MEDLINE]

3:

Microcirculatory oxygenation and shunting in sepsis and shock.

Ince C, Sinaasappel M.

Crit Care Med. 1999 Jul;27(7):1369-77. Review.

PMID: 10446833 [PubMed - indexed for MEDLINE]

4:

Opening the microcirculation: can vasodilators be useful in sepsis?

Buwalda M, Ince C.

Intensive Care Med. 2002 Sep;28(9):1208-17. Epub 2002 Jul 27. Review.

PMID: 12209267 [PubMed - indexed for MEDLINE]

5:

Clinical manifestations of disordered microcirculatory perfusion in severe sepsis.

Trzeciak S, Rivers EP.

Crit Care. 2005;9 Suppl 4:S20-6. Epub 2005 Aug 25. Review.

PMID: 16168070 [PubMed - indexed for MEDLINE]

6:

Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival.

Trzeciak S, Dellinger RP, Parrillo JE, Guglielmi M, Bajaj J, Abate NL, Arnold RC, Colilla S, Zanotti S, Hollenberg SM; Microcirculatory Alterations in Resuscitation and Shock Investigators.

Ann Emerg Med. 2007 Jan;49(1):88-98, 98.e1-2. Epub 2006 Nov 7.

PMID: 17095120 [PubMed - indexed for MEDLINE]

7:

Microvascular resuscitation as a therapeutic goal in severe sepsis.

Bateman RM, Walley KR.

Crit Care. 2005;9 Suppl 4:S27-32. Epub 2005 Aug 25. Review.

PMID: 16168071 [PubMed - indexed for MEDLINE]

8:

Mechanisms of critical illness--classifying microcirculatory flow abnormalities in distributive shock.

Elbers PW, Ince C.

Crit Care. 2006;10(4):221. Review.

PMID: 16879732 [PubMed - indexed for MEDLINE]

9:

Bench-to-bedside review: sepsis is a disease of the microcirculation.

Spronk PE, Zandstra DF, Ince C.

Crit Care. 2004 Dec;8(6):462-8. Epub 2004 Jun 16. Review.

PMID: 15566617 [PubMed - indexed for MEDLINE]

10:

How monitoring of the microcirculation may help us at the bedside.

Verdant C, De Backer D.

Curr Opin Crit Care. 2005 Jun;11(3):240-4. Review.

PMID: 15928473 [PubMed - indexed for MEDLINE]

11:

Resuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials.

Trzeciak S, Cinel I, Phillip Dellinger R, Shapiro NI, Arnold RC, Parrillo JE, Hollenberg SM; Microcirculatory Alterations in Resuscitation and Shock (MARS) Investigators.

Acad Emerg Med. 2008 May;15(5):399-413. Review.

PMID: 18439194 [PubMed - indexed for MEDLINE]

12:

Continuous thoracic epidural anesthesia improves gut mucosal microcirculation in rats with sepsis.

Daudel F, Freise H, Westphal M, Stubbe HD, Lauer S, Bone HG, Van Aken H, Sielenkämper AW.

Shock. 2007 Nov;28(5):610-4.

PMID: 17589385 [PubMed - indexed for MEDLINE]

13:

The microcirculation as a functional system.

Ellis CG, Jagger J, Sharpe M.

Crit Care. 2005;9 Suppl 4:S3-8. Epub 2005 Aug 25. Review.

PMID: 16168072 [PubMed - indexed for MEDLINE]

14:

The hemodynamic derangements in sepsis: implications for treatment strategies.

Marik PE, Varon J.

Chest. 1998 Sep;114(3):854-60. Review.

PMID: 9743178 [PubMed - indexed for MEDLINE]

15:

Effect of increased cardiac output on hepatic and intestinal microcirculatory blood flow, oxygenation, and metabolism in hyperdynamic murine septic shock.

Albuszies G, Radermacher P, Vogt J, Wachter U, Weber S, Schoaff M, Georgieff M, Barth E.

Crit Care Med. 2005 Oct;33(10):2332-8.

PMID: 16215389 [PubMed - indexed for MEDLINE]

16:

Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsis.

Boerma EC, van der Voort PH, Spronk PE, Ince C.

Crit Care Med. 2007 Apr;35(4):1055-60.

PMID: 17334238 [PubMed - indexed for MEDLINE]

17:

Microcirculatory dysfunction in sepsis: a pathogenetic basis for therapy?

Lehr HA, Bittinger F, Kirkpatrick CJ.

J Pathol. 2000 Feb;190(3):373-86. Review.

PMID: 10685071 [PubMed - indexed for MEDLINE]

18:

Targeted resuscitation strategies after injury.

Bilkovski RN, Rivers EP, Horst HM.

Curr Opin Crit Care. 2004 Dec;10(6):529-38. Review.

PMID: 15616397 [PubMed - indexed for MEDLINE]

19:

Nitroglycerin in septic shock after intravascular volume resuscitation.

Spronk PE, Ince C, Gardien MJ, Mathura KR, Oudemans-van Straaten HM, Zandstra DF.

Lancet. 2002 Nov 2;360(9343):1395-6.

PMID: 12423989 [PubMed - indexed for MEDLINE]

20:

Heterogeneous microcirculation in the rat small intestine during hemorrhagic shock: quantification of the effects of hypertonic-hyperoncotic resuscitation.

Vajda K, Szabó A, Boros M.

Eur Surg Res. 2004 Nov-Dec;36(6):338-44.

PMID: 15591741 [PubMed - indexed for MEDLINE]

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