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Items 1 - 20 of 105
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1:

Protein C as a surrogate end-point for clinical trials of sepsis.

Liu KD, Matthay MA.

Crit Care. 2008;12(2):139. Epub 2008 Apr 24.

PMID: 18492215 [PubMed - indexed for MEDLINE]

2:

Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated).

Shorr AF, Nelson DR, Wyncoll DL, Reinhart K, Brunkhorst F, Vail GM, Janes J.

Crit Care. 2008;12(2):R45. Epub 2008 Apr 4. Review.

PMID: 18394162 [PubMed - indexed for MEDLINE]

3:

Clinical trials in severe sepsis with drotrecogin alfa (activated).

Laterre PF.

Crit Care. 2007;11 Suppl 5:S5. Review.

PMID: 18269692 [PubMed - indexed for MEDLINE]

4:

Static and dynamic assessment of biomarkers in surgical patients with severe sepsis.

Lowry SF, Awad S, Ford H, Cheadle W, Williams MD, Qualy RL, McCollam JS, Bates BM, Fry DE; PROWESS Surgical Evaluation Committee.

Surg Infect (Larchmt). 2004 Fall;5(3):261-8.

PMID: 15684797 [PubMed - indexed for MEDLINE]

5:

[Clinical approach to the identification of patients suffering from severe sepsis with several organ failures for the administration of drotrecogin alfa (activated): from the PROWESS study to clinical practice]

Dhainaut JF, Payen DM, Bernardin G, Gérard JL, Martin C, Perrotin D, Regnier B.

Ann Fr Anesth Reanim. 2003 Dec;22 Spec No 1:53-64. Review. French. No abstract available.

PMID: 15359946 [PubMed - indexed for MEDLINE]

6:

Pharmacology, clinical efficacy, and safety of drotrecogin alfa (activated).

Rudis MI, Fish DN.

Pharmacotherapy. 2002 Dec;22(12 Pt 2):182S-195S. Review.

PMID: 12492225 [PubMed - indexed for MEDLINE]

7:

Effect of factor V Leiden polymorphism in severe sepsis and on treatment with recombinant human activated protein C.

Yan SB, Nelson DR.

Crit Care Med. 2004 May;32(5 Suppl):S239-46.

PMID: 15118525 [PubMed - indexed for MEDLINE]

8:

[Surgical patients with severe sepsis: first results of the PROWESS study. Demographic data]

Montravers P, Blaise M.

Ann Fr Anesth Reanim. 2003 Dec;22 Spec No 1:38-9. French. No abstract available.

PMID: 15359941 [PubMed - indexed for MEDLINE]

9:

Activated protein C (Xigris) treatment in sepsis: a drug in trouble.

Gårdlund B.

Acta Anaesthesiol Scand. 2006 Sep;50(8):907-10.

PMID: 16923083 [PubMed - indexed for MEDLINE]

10:

The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis.

Angus DC, Laterre PF, Helterbrand J, Ely EW, Ball DE, Garg R, Weissfeld LA, Bernard GR; PROWESS Investigators.

Crit Care Med. 2004 Nov;32(11):2199-206.

PMID: 15640631 [PubMed - indexed for MEDLINE]

11:

A retrospective observational study of drotrecogin alfa (activated) in adults with severe sepsis: comparison with a controlled clinical trial.

Wheeler A, Steingrub J, Schmidt GA, Sanchez P, Jacobi J, Linde-Zwirble W, Bates B, Qualy RL, Woodward B, Zeckel M.

Crit Care Med. 2008 Jan;36(1):14-23.

PMID: 18158435 [PubMed - indexed for MEDLINE]

12:

Drotrecogin alfa (activated) (recombinant human activated protein C) for the treatment of severe sepsis.

Bernard GR.

Crit Care Med. 2003 Jan;31(1 Suppl):S85-93. Review.

PMID: 12544981 [PubMed - indexed for MEDLINE]

13:

A blind clinical evaluation committee should, in theory, make data of a randomized clinical trial stronger, not weaker.

Carlet J.

Intensive Care Med. 2004 May;30(5):994; author reply 995. Epub 2004 Apr 9. No abstract available.

PMID: 15083270 [PubMed - indexed for MEDLINE]

14:

Activated protein C: beyond 28 days.

Manocha S, Walley KR.

Crit Care Med. 2004 Nov;32(11):2348-9. No abstract available.

PMID: 15640656 [PubMed - indexed for MEDLINE]

15:

Risks and benefits of activated protein C treatment for severe sepsis.

Warren HS, Suffredini AF, Eichacker PQ, Munford RS.

N Engl J Med. 2002 Sep 26;347(13):1027-30. No abstract available.

PMID: 12324562 [PubMed - indexed for MEDLINE]

16:

Drotrecogin alfa (recombinant human activated protein C) for the treatment of severe sepsis.

McCoy C, Matthews SJ.

Clin Ther. 2003 Feb;25(2):396-421. Review.

PMID: 12749504 [PubMed - indexed for MEDLINE]

17:

Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569].

Kinasewitz GT, Yan SB, Basson B, Comp P, Russell JA, Cariou A, Um SL, Utterback B, Laterre PF, Dhainaut JF; PROWESS Sepsis Study Group.

Crit Care. 2004 Apr;8(2):R82-90. Epub 2004 Feb 10.

PMID: 15025782 [PubMed - indexed for MEDLINE]

18:

Hospital mortality and resource use in subgroups of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial.

Laterre PF, Levy H, Clermont G, Ball DE, Garg R, Nelson DR, Dhainaut JF, Angus DC.

Crit Care Med. 2004 Nov;32(11):2207-18.

PMID: 15640632 [PubMed - indexed for MEDLINE]

19:

Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis.

Ely EW, Laterre PF, Angus DC, Helterbrand JD, Levy H, Dhainaut JF, Vincent JL, Macias WL, Bernard GR; PROWESS Investigators.

Crit Care Med. 2003 Jan;31(1):12-9.

PMID: 12544987 [PubMed - indexed for MEDLINE]

20:

Treating severe sepsis with drotrecogin alfa (activated).

Wyncoll D.

Hosp Med. 2003 Mar;64(3):168-72. Review.

PMID: 12669484 [PubMed - indexed for MEDLINE]

Items 1 - 20 of 105
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