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Opioid-induced constipation in intensive care patients: relief in sight?

Chappell D, Rehm M, Conzen P.

Crit Care. 2008;12(4):161. Epub 2008 Jul 1.

PMID: 18598388 [PubMed - in process]

Methylnaltrexone for opioid-induced constipation in advanced illness.

Thomas J, Karver S, Cooney GA, Chamberlain BH, Watt CK, Slatkin NE, Stambler N, Kremer AB, Israel RJ.

N Engl J Med. 2008 May 29;358(22):2332-43.

PMID: 18509120 [PubMed - indexed for MEDLINE]

Methylnaltrexone: MNTX.

[No authors listed]

Drugs R D. 2006;7(6):374-8. Review.

PMID: 17073520 [PubMed - indexed for MEDLINE]

Subcutaneous methylnaltrexone for the treatment of opioid-induced constipation in patients with advanced illness: a double-blind, randomized, parallel group, dose-ranging study.

Portenoy RK, Thomas J, Moehl Boatwright ML, Tran D, Galasso FL, Stambler N, Von Gunten CF, Israel RJ.

J Pain Symptom Manage. 2008 May;35(5):458-68.

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How safe and effective is methylnaltrexone for the treatment of opioid-induced constipation in advanced illness?

Foss J.

Nat Clin Pract Gastroenterol Hepatol. 2008 Nov 18. [Epub ahead of print]

PMID: 19015651 [PubMed - as supplied by publisher]

Incidence, prevalence, and management of opioid bowel dysfunction.

Pappagallo M.

Am J Surg. 2001 Nov;182(5A Suppl):11S-18S. Review.

PMID: 11755892 [PubMed - indexed for MEDLINE]

Effects of intravenous methylnaltrexone on opioid-induced gut motility and transit time changes in subjects receiving chronic methadone therapy: a pilot study.

Yuan CS, Foss JF, O'Connor M, Osinski J, Roizen MF, Moss J.

Pain. 1999 Dec;83(3):631-5.

PMID: 10568873 [PubMed - indexed for MEDLINE]

Constipation--modern laxative therapy.

Klaschik E, Nauck F, Ostgathe C.

Support Care Cancer. 2003 Nov;11(11):679-85. Epub 2003 Sep 20. Review.

PMID: 14505158 [PubMed - indexed for MEDLINE]

Methylnaltrexone for reversal of constipation due to chronic methadone use: a randomized controlled trial.

Yuan CS, Foss JF, O'Connor M, Osinski J, Karrison T, Moss J, Roizen MF.

JAMA. 2000 Jan 19;283(3):367-72.

PMID: 10647800 [PubMed - indexed for MEDLINE]

10:

A review of methylnaltrexone, a peripheral opioid receptor antagonist, and its role in opioid-induced constipation.

Shaiova L, Rim F, Friedman D, Jahdi M.

Palliat Support Care. 2007 Jun;5(2):161-6. Review.

PMID: 17578067 [PubMed - indexed for MEDLINE]

11:

The use of enteral naloxone to treat opioid-induced constipation in a pediatric intensive care unit.

Tofil NM, Benner KW, Faro SJ, Winkler MK.

Pediatr Crit Care Med. 2006 May;7(3):252-4.

PMID: 16575353 [PubMed - indexed for MEDLINE]

12:

Oral naloxone reverses opioid-associated constipation.

Meissner W, Schmidt U, Hartmann M, Kath R, Reinhart K.

Pain. 2000 Jan;84(1):105-9.

PMID: 10601678 [PubMed - indexed for MEDLINE]

13:

Pharmacologic management of constipation in the critically ill patient.

Patanwala AE, Abarca J, Huckleberry Y, Erstad BL.

Pharmacotherapy. 2006 Jul;26(7):896-902.

PMID: 16803421 [PubMed - indexed for MEDLINE]

14:

The relationship between opioid use and laxative use in terminally ill cancer patients.

Sykes NP.

Palliat Med. 1998 Sep;12(5):375-82.

PMID: 9924600 [PubMed - indexed for MEDLINE]

15:

Opioid-induced bowel dysfunction: pathophysiology and potential new therapies.

Kurz A, Sessler DI.

Drugs. 2003;63(7):649-71. Review.

PMID: 12656645 [PubMed - indexed for MEDLINE]

16:

Prophylaxis for opioid-induced constipation in elderly long-term care residents: a cross-sectional study of Medicare beneficiaries.

Max EK, Hernandez JJ, Sturpe DA, Zuckerman IH.

Am J Geriatr Pharmacother. 2007 Jun;5(2):129-36.

PMID: 17719515 [PubMed - indexed for MEDLINE]

17:

Methylnaltrexone mechanisms of action and effects on opioid bowel dysfunction and other opioid adverse effects.

Yuan CS.

Ann Pharmacother. 2007 Jun;41(6):984-93. Epub 2007 May 15. Review.

PMID: 17504835 [PubMed - indexed for MEDLINE]

18:

[Treament of morphine-induced constipation with oral naloxone]

Latasch L, Zimmermann M, Eberhardt B, Jurna I.

Anaesthesist. 1997 Mar;46(3):191-4. German.

PMID: 9163262 [PubMed - indexed for MEDLINE]

19:

Meeting the Challenges of Opioid-Induced Constipation in Chronic Pain Management - A Novel Approach.

Reimer K, Hopp M, Zenz M, Maier C, Holzer P, Mikus G, Bosse B, Smith K, Buschmann-Kramm C, Leyendecker P.

Pharmacology. 2008 Oct 28;83(1):10-17. [Epub ahead of print]

PMID: 18957874 [PubMed - as supplied by publisher]

20:

Opioid-induced or pain relief-reduced symptoms in advanced cancer patients?

Mercadante S, Villari P, Ferrera P, Casuccio A.

Eur J Pain. 2006 Feb;10(2):153-9.

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