2:
High-mobility group box-1 in ischemia-reperfusion injury of the heart.
Andrassy M, Volz HC, Igwe JC, Funke B, Eichberger SN, Kaya Z, Buss S, Autschbach F, Pleger ST, Lukic IK, Bea F, Hardt SE, Humpert PM, Bianchi ME, Mairbäurl H, Nawroth PP, Remppis A, Katus HA, Bierhaus A.
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PMID: 18574060 [PubMed - indexed for MEDLINE]
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Structural basis for the proinflammatory cytokine activity of high mobility group box 1.
Li J, Kokkola R, Tabibzadeh S, Yang R, Ochani M, Qiang X, Harris HE, Czura CJ, Wang H, Ulloa L, Wang H, Warren HS, Moldawer LL, Fink MP, Andersson U, Tracey KJ, Yang H.
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A cardiovascular drug rescues mice from lethal sepsis by selectively attenuating a late-acting proinflammatory mediator, high mobility group box 1.
Li W, Li J, Ashok M, Wu R, Chen D, Yang L, Yang H, Tracey KJ, Wang P, Sama AE, Wang H.
J Immunol. 2007 Mar 15;178(6):3856-64.
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Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects.
O'Connor KA, Hansen MK, Rachal Pugh C, Deak MM, Biedenkapp JC, Milligan ED, Johnson JD, Wang H, Maier SF, Tracey KJ, Watkins LR.
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The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion.
Tsung A, Sahai R, Tanaka H, Nakao A, Fink MP, Lotze MT, Yang H, Li J, Tracey KJ, Geller DA, Billiar TR.
J Exp Med. 2005 Apr 4;201(7):1135-43. Epub 2005 Mar 28.
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IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism.
Rendon-Mitchell B, Ochani M, Li J, Han J, Wang H, Yang H, Susarla S, Czura C, Mitchell RA, Chen G, Sama AE, Tracey KJ, Wang H.
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High mobility group 1 B-box mediates activation of human endothelium.
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Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury.
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